We note that Kalydeco is already approved in the US, EU and Canada. Kalydeco, which delivered revenues of $171.6 million in 2012, is off to a strong start and should continue performing well in 2013.
Vertex Pharma reported rapid uptake in a major part of eligible patients in the US in the first quarter of 2013. While US sales were $50 million, ex-US sales were about $12 million in the first quarter of 2013. Sales should benefit from reimbursement in additional European countries and launch in new markets.
We note that Vertex Pharma is also working on expanding Kalydeco�� label. Kalydeco is currently in three phase III studies in which it is being evaluated as a monotherapy in CF patients (��6 years of age) who have at least one copy of the R117H mutation, in CF patients (��6 years of age) who have at least one non-G551D CFTR gating mutation and in children with CF (2 to 5 years old) who have a gating mutation.
Top 10 Industrial Conglomerate Stocks To Buy For 2015: Allison Transmission Holdings Inc (ALSN)
Allison Transmission Holdings, Inc. (Allison), incorporated on June 22, 2007, designs and manufactures commercial and military fully-automatic transmissions. The Company is a manufacturer of fully-automatic transmissions for medium- and heavy-duty commercial vehicles, medium- and heavy-tactical the United States military vehicles and hybrid-propulsion systems for transit buses. Allison transmissions are used in a range of applications, including on-highway trucks (distribution, refuse, construction, fire and emergency), buses (primarily school and transit), motorhomes, off-highway vehicles and equipment (energy and mining) and military vehicles (wheeled and tracked). In January 2014, the Company opened a facility in the Netherlands to serve customers across Europe, the Middle East and Africa.
Allison transmissions are sold under the Allison Transmission brand name and remanufactured transmissions are sold under the ReTran brand name. The Company has 12 transmission product lines with over 100 different product models. Allison transmissions are included in more than 2,500 vehicle configurations, which are compatible with more than 500 combinations of engine brands, models and ratings globally. In addition to the Company's product offerings, the Company has products under development, including the TC10, a Class 8 metro truck fully-automatic transmission, and the H 3000 and the H 4000 hybrid-propulsion systems designed for use in medium- and heavy-duty commercial trucks and buses.
North America
The Company is a manufacturer of fully-automatic transmissions for the on-highway medium- and heavy-duty commercial vehicle markets in North America. The Company's core North American on-highway market includes Class 4-5, Class 6-7 and Class 8 straight trucks, conventional transit, shuttle and coach buses, school buses and motorhomes. Class 8 trucks are subdivided into two markets: straight and tractor. The Company sells its transmissions in the North American on-highway mar! ket to original equipment manufacturers (OEMs), including Blue Bird, Daimler, Hino, Navistar, PACCAR, Spartan Motors and Volvo. These OEMs, in turn, install the Company's transmissions in vehicles in which its transmission is either the exclusive transmission available or is specifically requested by end users who are choosing between a manual transmission, an AMT or a fully-automatic transmission. The Company's vehicle class in North America include Class 4-5 Trucks, Class 6-7 Trucks, Class 8 Straight Trucks, Buses and
Motorhomes
Class 4-5 trucks are used in urban applications, including distribution, commercial lease and rental, as well as ambulance. The Company is the transmission supplier to the Navistar Class 4-5 TerraStar truck. Class 6-7 trucks are used in urban applications, including larger distribution, commercial lease and rental, ambulance, rescue and fire trucks. The Company's transmissions are used in Class 6-7 buses. The Company supplies its transmissions for all of the school buses produced in North America. The bus market also encompasses non-hybrid transit and conventional coach and shuttle buses. The Company sells its transmissions for use in larger motorhomes ( types A). The Company typically sells to the chassis manufacturers, such as Navistar and Daimler, that supply body manufacturers, such as Thor Industries, Winnebago Industries and Fleetwood RV. As of December 31, 2012, the Company has delivered over 5,000 H 40/50 EP hybrid-propulsion transit bus systems globally to 246 cities in 14 countries. The Company's customers in this North American end market are typically city, state and federal governmental entities. The Company has provided products used in vehicles and equipment, which serve energy, mining and construction applications. Its customers include Halliburton Company, Baker Hughes, Weatherford International, National Oilwell Varco, and Key Energy Services. The Company also provides heavy-duty transmissions used in mining trucks, specialty and co! nstructio! n vehicles. Mining applications include trucks used to haul various commodities and other products, including rigid dump trucks, underground trucks and long-haul tractor trailer trucks with load capacities between 40 to 110 tons. Specialty vehicles using the Company's heavy-duty transmissions include airport rescue and firefighting vehicles and heavy-equipment transporters.
Outside North America
The Company is a manufacturer of fully-automatic transmissions for the commercial vehicle markets outside of North America. Within Europe, the Company serves Western European developed markets, as well as Russian and Eastern European emerging markets. The Company's on-highway customers in these markets are Daimler, Iveco, Scania, and Volvo. Fully-automatic transmission technology has approximately a 6% market share in European truck applications. The Company supplies transmissions to European OEMs. The Company is the exclusive transmission in refuse chassis with Daimler, Dennis Eagle and Renault SA. The Company also supply mining OEMs, such as Atlas Copco UK, Perlini Equipment, Sandvik AB and Terex. As of December 31, 2012, in China, the Company is the provider of fully-automatic commercial vehicle transmissions with a substantial installed base of over 45,000 Allison transmissions, including 30,000 units in transit buses, operated by 90 different bus fleets in 55 cities. The Company's off-highway transmissions are also used in China for energy, mining and construction, by OEM customers including 4th Petroleum and Yantai Jereh Oilfield Services Group Co. in energy applications and Qinhuangdao Tolian Speciality Transporter Co., Sany Group Co. and North Hauler in mining and construction applications. Australia and South Korea have OEMs with domestic production capabilities for which the Company is a supplier, including Iveco, Hyundai Motor Company and Daewoo International Corporation.
Military
The Company sells all of the transmissions for medium- and heavy-tac! tical whe! eled vehicle platforms, including the Family of Medium Tactical Vehicles, Armored Security Vehicles, Heavy Expanded Mobility Tactical Trucks, Heavy Equipment Transporters, Palletized Loading Systems, M915 Series Trucks, Medium Tactical Vehicle Replacements and the Logistic Vehicle System Replacement. In addition, the Company supplied transmissions for Mine-Resistant Ambush Protected (MRAP) Vehicles and the MRAP All Terrain Vehicle and for all three potential manufacturers of the Joint Light Tactical Vehicles. Transmissions for the Company's wheeled vehicle platforms are sold to OEMs, including BAE, Daimler, General Dynamics Land Systems, Oshkosh, Navistar and Textron Marine & Land Systems.
The Company is the supplier on two of the three key tracked vehicle platforms, the Abrams tank and the M113 family of vehicles, which are sold directly to the United States military. Additionally, the Company sells parts kits to licensees for the production of transmissions for tracked vehicles manufactured outside North America. The Company has been selected as the transmission supplier for the prime contractors bidding for the United States Army ground combat vehicle.
Service Parts, Support, Equipment and Other (Aftermarket)
Aftermarket provides the Company with a source of revenues as the installed base of vehicles and equipment utilizing the Company's transmissions. The Company has assembled a global network of approximately 1,400 distributor and dealer locations to sells, service and support its transmissions. As part of the Company's brand strategy, its independent distributors and dealers are required to sell genuine Allison-branded parts. The Company offers remanufactured transmissions under its ReTran brand. The Company also provides support equipment to its OEMs to assist in installing new Allison transmissions into vehicles.
The Company competes with Ford Motor Company, Eaton Corp., Voith GmbH, ZF Friedrichshafen AG, BAE, Caterpillar Inc., Twin Disc, Inco! rporated,! Komatsu, Ltd., Aisin Seiki Co., Ltd., JATCO Ltd, Mitsubishi Fuso Truck and Bus Corporation, Hino, Isuzu and Nissan Diesel, Danyang Winstar Auto Parts Co., Ltd., Tata, Ashok Leyland, JCBL Ltd., Asia Motor Works Limited, BEML, Renk AG and L-3 Communications Corporation.
Advisors' Opinion:- [By Ben Levisohn]
2Q14 Machinery results are likely to reflect what we view as a still mixed but improving macroeconomic environment that we think could support pockets of strength in Machinery end markets. In particular, we think both North American truck and North American energy markets continue to improve while global construction markets look supportive of continued solid/better-than-expected results (mostly from improved margin) in Caterpillar’s Construction segment. Solid truck, energy and construction markets seem supportive of earnings for Caterpillar as well as truck suppliers Cummins (CMI) and Allison Transmission Holdings (ALSN)…
- [By Rich Duprey]
Approving an increase in the quarterly cash dividend paid to shareholders, transmission manufacturer Allison Transmissions (NYSE: ALSN ) �announced today that its board of directors doubled the payout from�$0.06�per share to�$0.12�per share while also providing preliminary estimates for its first quarter, which ended March 31.
Top Performing Stocks To Invest In Right Now: Canterbury Park Holding Corporation(CPHC)
Canterbury Park Holding Corporation conducts pari-mutuel wagering operations and hosts unbanked card games at its Canterbury Park racetrack and card room facility in Shakopee, Minnesota. The company operates in three segments: Horse Racing, Card Room, and Concessions. The Horse Racing segment operates year-round pari-mutuel wagering on simulcast horse races, and live thoroughbred and quarter horse races held on a seasonal basis. The Card Room segment offers unbanked card games, which include poker and casino games. The Concessions segment provides food and beverage services for simulcast and live racing, and the card room, as well as for the special events. The company also offers facilities for special events, such as snowmobile races, arts and crafts shows, trade shows, concerts, fundraisers, automobile shows and competitions, vehicle and boat storage, and private parties. In addition, it provides advertising signage space; leases excess parking lot space for various aut omotive activities and vehicle storage; and sells various daily pari-mutuel publications. Canterbury Park Holding Corporation was founded in 1994 and is based in Shakopee, Minnesota.
Advisors' Opinion:- [By Monica Wolfe]
Lastly, Gabelli increased his position in Canterbury Park Holding (CPHC). Gabelli upped his stake 3.18% by purchasing a total of 13,824 shares. He bought these shares at an average price of $11.11 per share, and since then the price per share is up about 3%. Gabelli now holds 447,944 shares, representing 10.74% of the company�� shares outstanding.
- [By Sally Jones]
Canterbury Park Holding Corporation (CPHC) ��Market Cap $46.35 Million
Canterbury Park Holding Corporation is up 2% over 12 months. The company has a market cap of $46.35 million; its trades around $11.16 with a P/E ratio of 59.30 and a P/B of 1.70.
Top Performing Stocks To Invest In Right Now: Ressources Minieres Radisson Inc (RDS)
Ressources Minieres Radisson Inc., formerly Radisson Mining Resources Inc., is in the process of exploring mining properties. The Company has portfolio of four properties, covering a total area of 2,946 hectares. Three of these properties are located in Quebec and one in Ontario. The Company owns a 100% interest in O��rien 576-hectare property. The Company also owns 100% interest in Kewagama 111.7-hectare property. The Company�� O��rien/Kewagama project is located in the Cadillac-Malartic area, within the Abitibi gold belt. It consists of 36 claims covering an area of 729 hectares. The O��rien/Kewagama project lies approximately five kilometer west of Agnico-Eagle�� Lapa gold mine, also centred on the Cadillac Break, and approximately four kilometer southwest of Agnico-Eagle�� Laronde mine, over 3,000 meters (10,000 feet) in depth. Advisors' Opinion:- [By Jim Jubak]
The latest news to make me wonder if the stock has hit a bottom came out in an interview that the CEO of Royal Dutch Shell (RDS) gave to the Financial Times yesterday, April 1. CEO Ben Van Beurden said that in an effort to make a profit in the company�� North American operations, the company had launched ��roject Mosaic��to cut costs in its North American shale operations, by sourcing more equipment from cheaper Asian suppliers.
Top Performing Stocks To Invest In Right Now: Antofagasta PLC (ANTO)
Antofagasta plc (Antofagasta) is a Chile-based copper mining company with interests in transport and water distribution. The Company operates in three segments: Mining, Transport and Water. Antofagasta is a holding company that operates through its subsidiaries, associates and joint ventures. The principal activities of the Company are copper mining (including exploration and development), the transportation of freight by rail and road and the distribution of water. Its mining operations produce copper with by-products of gold, molybdenum and silver. Its activities are mainly concentrated in Chile. The Company�� segments include Los Pelambres, Esperanza, El Tesoro, Michilla, Antucoya, Exploration and evaluation, Railway and other transport services, Water concession, and Corporate and other items. Advisors' Opinion:- [By Sarah Jones]
Among commodity producers, Antofagasta (ANTO) Plc rose 1.4 percent to 904 pence as base metals advanced in London. Glencore Xstrata added 3.2 percent to 315.9 pence and Rio Tinto Group increased 1 percent to 2,786 pence.
- [By Sarah Jones]
Rio Tinto, the world�� second-largest mining company, fell 2.7 percent to 2,959.5 pence. Anglo American dropped 2.6 percent to 1,606 pence and Antofagasta Plc (ANTO), which mines for copper in Chile, retreated 3.9 percent to 916 pence.
- [By Namitha Jagadeesh]
British American Tobacco Plc and Imperial Tobacco Group Plc (IMT) each lost at least 1.5 percent as American peer Philip Morris International Inc. forecast 2014 profit growth below its long-term target. Antofagasta Plc (ANTO) and Vedanta Resources Plc (VED) followed miners lower, sliding at least 2 percent. Johnson Matthey Plc (JMAT) gained 3.9 percent after posting better-than-forecast profit and raising its dividend.
- [By Sarah Jones]
Vedanta Resources slumped 6.5 percent to 1,026 pence as copper tumbled on the London Metal Exchange to its lowest price since July 2010. Antofagasta Plc (ANTO), the copper producer controlled by Chile�� Luksic family, slid 3 percent to 813 pence and Anglo American Plc (AAL) lost 4 percent to 1,297.5 pence.
Top Performing Stocks To Invest In Right Now: SPDR S&P International Consumer Discretionary Sector ETF (IPD)
SPDR S&P International Consumer Discretionary Sector ETF (the Fund) seeks to provide investment results that correspond generally to the total return performance of the S&P Developed Ex-U.S. BMI Consumer Discretionary Sector Index (the Index), an index that tracks the consumer discretionary sector of developed global markets outside the United States. The Index represents the non-United States consumer discretionary sub-industry of developed countries included in the S&P Broad Market Index (the Global BMI Index). The Global BMI Index captures the full universe of institutionally investable stocks in developed and emerging markets with float-adjusted market capitalizations of at lease $100 million. The Fund�� investment advisor is SSgA Funds Management, Inc. Advisors' Opinion:- [By WilliamBriat]
The SPDR S&P International Consumer Discretionary Sector (NYSE: IPD) is an ETF that tracks the consumer discretionary sector of developed global markets. Holdings include luxury brand stock juggernaut LVMH Moët Hennessy – Louis Vuitton SA and Swedish luxury brand stock multinational retail clothing company H & M Hennes & Mauritz AB.
Top Performing Stocks To Invest In Right Now: Fomento de Construcciones y Contratas SA (FCC)
Fomento de Construcciones y Contratas SA (FCC) is a Spain-based company, which is primarily engaged, together with its subsidiaries in the construction and environmental services sector. The Company�� activities include the collection, treatment and elimination of solid urban waste, street cleaning, sewer system maintenance, green areas and buildings maintenance, urban transport, treatment and elimination of industrial waste, full-service water supply management and cement manufacture. The Company is also active in the real estate development, as well as in the renewable energy industry. In addition, the Company is a parent of Grupo FCC, a group which comprises a number of controlled entities. Advisors' Opinion:- [By Quick Pen]
The Federal Communications Commission (FCC) and the Department of Justice (DoJ) do not want the number of players in the telecom sector to shrink below four ��Verizon, AT&T, Sprint, and T-Mobile. To this Sprint�� Son argues that the industry already has four players ��Verizon that purchased Vodafone�� stake in it, AT&T which plans to acquire DirecTV (DTV), and Comcast (CMCSA); Sprint would be the fourth one. But these antitrust issues have been a challenge for Sprint.
- [By Live Investor]
What does the FCC have to say? The regulator�� reaction is nothing surprising. After Son met the Federal Communications Commission (FCC) to convince them about the prospects of the proposed deal, Reuters reported that FCC chairman Tom Wheeler wasn�� quite impressed and had dubious thoughts on it.
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